Statistics for Egg Becoming a Baby Based on Rating

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Table of contents

  • Main points
  • Department 1. IVF birth rates have increased for patients nether 43 years
  • Department 2. Birth rates were to a higher place twenty% per embryo transferred on average in the first three cycles
  • Section 3. Using donor eggs can event in high birth rates for older patients, but they are non widely used
  • Section 4. The multiple nascence rate decreased further to viii% in 2018
  • Section 5. Transferring more than i embryo could result in a multiple birth rate over 30%
  • Section vi. Embryo and egg storage have increased as freezing becomes more mutual
  • Section seven. NHS-funded cycles decreased in many English regions
  • Department eight. Fewer patients had their kickoff IVF bicycle funded by the NHS
  • Virtually our information

Main points

  • About 54,000 patients had 68,724 fresh and frozen in-vitro fertilisation (IVF) cycles and 5,651 donor insemination (DI) cycles at HFEA licensed fertility clinics in the United kingdom in 2018.
  • In 2018, the average birth rate per embryo transferred for all IVF patients was 23% and rates accept steadily increased over time for all patients anile nether 43.
  • In 2018, birth rates for patients beneath 35 were 31% per embryo transferred, compared to below 5% for patients 43 and above when using their own eggs.
  • The alive birth rate per embryo transferred remains to a higher place twenty% for each of the first three cycles of IVF treatment.
  • Donor eggs can considerably increase the chance of a live birth to higher up 25%, but only 18% of patients aged 40 and older used donor eggs in 2018.
  • The multiple birth rate decreased to 8% in 2018 for the first fourth dimension.
  • Implanting more than one embryo has no significant touch on on the chance of a live birth but results in a 32% multiple birth rate for patients under 35.
  • Since 2013, the number of egg and embryo storage cycles increased fivefold to just under 9,000 cycles in 2018 as freezing techniques improved and have become more commonplace.
  • The level of NHS funding for fertility handling varies across the Uk with sixty% of cycles funded by the NHS in Scotland and falling to less than 30% in some parts of England.

1. IVF nascence rates take increased for patients nether 43 years

About 54,000 patients had 68,724 fresh and frozen in-vitro fecundation (IVF) cycles and 5,651 donor insemination (DI) cycles at HFEA licensed fertility clinics in the U.k. in 2018. Later years of rapid growth in the number of treatment cycles, these have begun to stabilise.

Birth rates from IVF have steadily increased over fourth dimension with the average nativity rate per embryo transferred at 23% in 2018. Patients under 35 had the highest nascence rate per embryo transferred at 31% in 2018, compared to just ix% when the HFEA was established in 1991.

The average age of an IVF patient was 35.3 years in 2018; age is a central factor to consider when looking at nascence rates, as fertility decreases with age. In 2018, nativity rates per embryo transferred were 25% for patients aged 35-37, 19% for patients aged 38-39, and 11% for patients anile xl-42.

Clinical improvements have led to increased chances of a live birth for all patients below 43 years old. In 2018, patients aged 40-42 had a higher chance of a live birth (xi% per embryo transferred) than patients aged nether 35 in 1991 (ix% per embryo transferred). Patients aged 43 and above have consistently had nascence rates below 5% per embryo transferred when using their ain eggs. In department 3 nosotros discuss how donor eggs can increase chances of success for older patients to higher up 20% on average.


Figure one. Birth rates have increased for all patients below 43 years of age since 1991

Nascency rates per embryo transferred using patient eggs by historic period band, 1991-2018

This line graph shows the trend in live birth rate per embryo transferred by patient age bands per year from 1991 to 2018 for IVF treatment cycles. Live birth rates per embryo transferred have risen for all age bands since 1991, although patients 43 and over had very little change and remain below 5%. The highest birth rate is seen with younger age bands. In 2018, patients under 35 had a birth rate of 31%, patients 35-37 had a birth rate of 25%, patients 38-39 had a birth rate of 19%, and patients 40-42 had a birth rate of 11%.

Effigy 1 Notation: This data includes treatment now only, IVF, Patient egg. It excludes fresh and frozen PGD and PGS, surrogacy, and cycles where pregnancy was recorded but not consequence.

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two. Birth rates were above 20% per embryo transferred on average in the first 3 cycles

On average, about 1 in every iv embryos transferred resulted in a live nativity in 2018. Equally a event, many patients volition have more than one circular of embryo transfer; the average patient has three rounds.

The figure below shows the chances of a live birth by cycle number in 2018. The boilerplate age of a patient on their first cycle was 34.4 (green line) and their take chances of having a live birth on that wheel was 26% per embryo transferred (blue column). By contrast, the average age of a patient on their 10th bicycle was 38.9 and their chance of having a live birth on that cycle was 12% per embryo transferred.

The birth rate remains to a higher place 20% per embryo transferred for each of the commencement three cycles and steadily decreases with each new cycle. The reason the average birth rate is lower in later on cycles is related to the average patient age, as older patients have lower nascence rates and therefore require more cycles (see section 1).


Figure 2. Birth rates per embryo transferred were in a higher place 20% on average in offset three IVF cycles

Birth rates per embryo transferred using patient eggs by cycle number and patient historic period, 2018

This combination chart shows the live birth rates per embryo transferred by IVF cycle number in 2018 in bars with average patient age overlayed in a line. The graph shows that the live birth rate per embryo transferred decreases by IVF cycle number, while the average patient age increases. The first three IVF cycles have a live birth rate above 20% per embryo transferred and it slowly drops as cycle number increases to about 14% for patients on their 10th IVF cycle. The average age for patients increases from just below 35 years of age on the first IVF cycle to almost 39 on the 10th cycle.

Figure 2 Note: This information includes treatment now but, IVF, Patient egg. Information technology excludes fresh and frozen PGD and PGS, surrogacy, and cycles where pregnancy was recorded but not outcome.

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three. Using donor eggs tin can result in loftier birth rates for older patients, but they are not widely used

Birth rates decrease with age where patients use their ain eggs in treatment. In 2018, nativity rates for patients below 35 were 31% per embryo transferred, compared to beneath 5% for patients 43 and above.

However, birth rates remained college (above 25%) for all ages when donor eggs were used as egg donors are five years younger on boilerplate (xxx.two) than IVF patients (35.vi).


Effigy iii. Birth rates remain above 25% for all ages where donor eggs are used

Birth rates per embryo transferred by age bands and egg source, 2018

This bar chart shows the live birth rate per embryo transferred by patient age bands and source of egg (patient eggs or donor eggs). This chart shows that when using patient eggs, live birth rates per embryo transferred decrease with age from over 30% for patients under 35 to below 5% for patients 43 and over. When using donor eggs live birth rates per embryo transferred are similar for all age groups and remains above 25% per embryo transferred.

Figure 3 Notation: This data includes handling now merely, IVF, Patient egg. It excludes fresh and frozen PGD and PGS, surrogacy, and cycles where pregnancy was recorded only non outcome.

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Although it is clear from the effigy above that donor eggs can considerably increase the take chances of a alive nascence for patients twoscore years of historic period and older, only 18% of patients in this age group used donor eggs in 2018. In particular, while birth rates were comparably low for patients aged 43-44 (5%) and patients above 44 (4%) using their own eggs, patients above 44 years were 3 time more likely to employ donor eggs.

Of all patients undergoing IVF handling in 2018, 94.4% were in heterosexual relationships, 3.1% were in female same-sexual practice relationships, 2.0% had no partner and 0.5% acted every bit surrogates – with little change compared to 2017. While accounting for less than 5.5% of all IVF treatments, single patients, those in female same-sex relationships and surrogates accounted for 46% of all IVF cycles using donor gametes in patients under twoscore.


Figure 4. Donor eggs are used about past those patients over 44

Proportion of IVF cycles using donor sperm/eggs by age ring, 2018

This bar chart shows the proportion of donor sperm and egg use for various age bands. Proportion of IVF cycles using donation increases with patient age. Under 10% of IVF cycles for patients under 35 used donor eggs and/or sperm, compared to almost 70% for patients over 44 years of age.

Figure iv Note: This information includes treatment now and IVF only.

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4. The multiple birth charge per unit decreased further to 8% in 2018

Multiple births are the biggest unmarried wellness take a chance from IVF to mothers and babies. In 2017, the 10% multiple birth rate target was accomplished for the first time nationally, but not across all age groups. In 2018, farther progress was made, as the 10% target was reached across all age groups and nationally only viii% of IVF births resulted in a multiple birth.


Figure 5. The 10% multiple birth target has been reached in all patient age groups

Multiple birth rates past historic period group, 2017 and 2018

This bar chart shows the multiple birth rate for various age bands for 2017 and 2018. The chart shows that the multiple birth rate has decreased for all age groups from 2017 to 2018, with all age groups now below the 10% sector target. Multiple birth rates are lowest for younger and older patients for both years, with patients 38-39 having the highest multiple birth rate of 11% in 2017 and 9% in 2018.

Figure 5 Note: This data includes handling now and IVF only. It excludes cycles where pregnancy was recorded only not issue.

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5. Transferring more than i embryo could result in a multiple birth rate over 30%

For each patient, the run a risk of a multiple birth is determined by the number of embryos put back and whether donor eggs were used. Our figures show that putting more than one embryo back has no meaning bear upon on the chance of a live birth just tin can considerably increment the risk of a multiple nascence.

Equally the effigy beneath shows, the risk of a multiple birth in IVF is comparable to natural formulation (two%), when only a single embryo is put back. Where two embryos were transferred, all the same, in that location was a 32% risk of a multiple birth for patients nether 35, without an increase in the chance of a live birth. In 2018, 21% of IVF cycles in patients under 35 had a double embryo transfer.

The conclusion to transfer more than 1 embryo at a fourth dimension should also consider the egg source. When two embryos were transferred, a 44-yr-quondam patient using donor eggs had about the same multiple birth risk as a 35-twelvemonth-one-time using their ain eggs. Of all cycles using donor eggs in patients 40 and over in 2018, 18% transferred back more than than one embryo.


Effigy six. Single embryo transfers are the safest pick for patients of all ages

Multiple birth rate by egg source and number of embryos transferred, UK, 2018

This bar chart shows the multiple birth rate in IVF treatment cycles by patient age bands, egg source (donor eggs or patient eggs) and the number of embryos transferred (one or two). Multiple birth rates for single embryo transfers are between 0% and 2% for all age groups and egg sources. Multiple birth rates for double embryo transfers are highest for younger patients when patient eggs are used at about 31% for patients under 35, decreasing to about 13% for patients over 44 years of age. For double embryo transfers using donor eggs, the highest multiple birth rates are seen with the youngest and oldest patients, with patients under 35 having a multiple birth rate around 31% and patients over 44 having a multiple birth rate of about 29%.

Figure 6 Note: This data includes treatment now and IVF but. Information technology excludes cycles where pregnancy was recorded but not event.

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half dozen. Embryo and egg storage have increased equally freezing becomes more common

The majority of patients using fertility services practice so with the intention of trying to excogitate equally soon as possible. However, at that place are other reasons people may use fertility services: to store their eggs and/or embryos for futurity use for fertility preservation; or to donate their eggs, sperm or embryos for use by another patient. While handling cycles increased by 12% betwixt 2013 and 2018, storage cycles increased much more than quickly, increasing by 523% from i,500 cycles in 2013 to just under 9,000 in 2018.

Equally freezing techniques have improved, a typical patient today will have a unmarried, fresh embryo transferred in their first cycle and whatsoever additional embryos created will be stored for use in subsequent frozen embryo transfers. Elective freeze-all cycles – where all fresh embryos are frozen after IVF to be used in later cycles – have as well get more than common. Equally a result, fresh embryo transfers decreased past eleven% between 2013 and 2018, while frozen embryo transfers almost doubled and accounted for 38% of all IVF cycles in 2018.


Table 1. Egg and embryo storage as well as frozen embryo IVF cycles are the fastest growing activities

Number of cycles past intended action, UK, 2013 and 2018
2013 2018 % alter
Fresh embryo transfer 48,391 42,835 -xi%
Frozen embryo transfer thirteen,421 25,889 +93%
Donor insemination 4,642 five,651 +22%
Treatment total 66,454 74,375 +12%
Embryo storage 871 vii,031 +707%
Egg storage 569 1,933 +240%
Storage total i,440 8,964 +523%
Donation i,393 1,916 +38%
Egg share 765 381 -50%
Donation total two,158 2,297 +6%

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vii. NHS-funded cycles decreased in many English regions

In 2018 in Scotland, 60% of handling was NHS-funded, compared to 45% in Northern Ireland, 41% in Wales and 35% in England. In Scotland, Wales and Northern Ireland, the level of funding is set nationally. In England, funding is locally determined by Clinical Commissioning Groups (CCGs) leading to considerable regional variation in funding, as seen in the table below. In England, many CCGs take reduced funding for fertility treatment and as a result, the share of IVF cycles funded by the NHS has declined beyond nearly regions. The biggest decreases were seen in the E of England likewise as Yorkshire and the Humber, decreasing the England-broad share to 35% (41% in 2013).


Table 2. Funding trends are diverging nationally and regionally, with the overall number of NHS funded cycles declining

NHS funding of IVF cycles in UK nations and English regions, 2018
UK nation % of cycles funded by NHS
IVF cycles in 2018 2013 2018
England 59,153 41% 35%
London 22,406 29% 27%
N Due west England 8,319 51% 55%
South East England vii,521 42% 32%
West Midlands iv,370 47% 40%
Yorkshire and Humber three,961 45% 26%
East Midlands iii,569 37% 34%
East of England 3,748 55% 26%
South West England 2,943 fifty% 41%
N East England 2,316 60% threescore%
Scotland five,060 51% 60%
Wales 2,689 23% 41%
Northern Ireland 1,853 45% 45%

Tabular array ii Notation: This information includes treatment now and IVF only

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8. Fewer patients had their first IVF bicycle funded by the NHS

As discussed in section 7, many English language regions have seen a decrease in the proportion of treatments funded by the NHS. As a result, approximately 2,000 fewer patients had their first circular of treatment funded by the NHS in 2018 compared to 2017, while treatments in the private sector connected to grow. In 2018, 52% of get-go IVF cycles were funded by the NHS, compared to 58% in 2017.


Effigy 7. Start cycles are nigh likely to be NHS funded, just this has decreased over time

Number of cycles by funding type and bicycle number, UK, 2009-2018

This line chart shows number of first, second and third IVF cycles by funding type (NHS or private). First IVF cycles have mainly been funded by the NHS, but this number has decreased from almost 16,000 cycles to 13,000 cycles from 2017 to 2018. Although first cycle NHS cycles are decreasing, there has not been much change in privately-funded first cycles. Second and third IVF cycles have mainly been funded privately and this has been steadily increasing since 2013.

Figure 7 Note: This data includes treatment now and IVF only

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About our data

The information that nosotros publish is a snapshot of data provided to us past licensed clinics. The figures supplied in this written report are from our data warehouse containing Register data as at 07/01/2020. Nosotros have excluded approximately 850 cycles due to technical issues at ane heart that resulted in reporting errors. Results are published according to the year in which the bike was started. For further information, please see our quality and methodology study.


Contact us regarding this publication

Media: press.function@hfea.gov.united kingdom of great britain and northern ireland

Statistical: intelligenceteam@hfea.gov.uk

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Source: https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/

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